The Distribution of Fetal Nuchal Translucency Thickness in Normal Korean Fetuses
نویسندگان
چکیده
The aim of present study was to establish normative data for the distribution of nuchal translucency (NT) thickness in normal Korean fetuses. The data were collected from pregnant women with singleton pregnancies in whom fetal ultrasound was performed and the fetal NT thickness was measured between 11 and 14 weeks of gestation. Among them, a total of 2,577 fetuses with a known normal outcome were included in this study. The distribution of multiple of median (MoM) values of the NT thickness with crown-rump length (CRL) in 10-mm intervals and the 95th percentile of MoM were calculated with the linear regression method. The present study showed that NT measurements increase with increasing CRL and a false positive rate increases with increasing gestational age. Therefore, a fixed cut-off point through the first trimester was not appropriate and each NT measurement should be examined according to the gestational age. The present study offers normative data of the fetal NT thickness in a Korean population, which can be used as reference for screening chromosomal aberrations or other congenital abnormalities in the first trimester.
منابع مشابه
I-44: Increased Nuchal Translucency at 11-14 Weeks of Gestation As A Marker for Adverse Pregnancy Outcomes
Background: To evaluate the association of increased fetal nuchal translucency( NT) and adverse pregnancy outcomes. Materials and Methods: In a prospective study, 2221 women who were conceived after Assisted Conception were investigated by sonography independent of multiplicity between 11 and 13 weeks' gestation. We performed 2899 NT examinations during the study period(21 March 2010 to 21...
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Objective To examine the association between increased nuchal translucency thickness and major cardiac defects in chromosomally normal fetuses. Setting Tertiary referral unit for fetal medicine and fetal
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Increased fetal nuchal translucency thickness at 10-14 weeks of gestation is a common phenotypic expression of fetal chromosomal defects, structural abnormalities and genetic syndromes. This study reports on the prevalence of structural abnormalities and genetic syndromes in 4116 chromosomally normal pregnancies with increased fetal nuchal translucency thickness and reviews the relevant literat...
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